Публікації (репозитарій) Архів - Сторінка 12 з 39 - ІМВ НАН України 🇺🇦

Phenotypic and Genotypic Criteria for the Screening of Highly Active S-Type Pyocins Pseudomonas aeruginosa Producers

Bacteriocins of Pseudomonas aeruginosa, especially S-type pyocins, show high efficiency as analogs of antimicrobial drugs. Various screening methods can be used to identify producers of highly active pyocins, but there are no clear criteria for selecting perspective strains. The aim of this work was to determine criteria that can be Читати далі

Guanidinium-Containing Oligomer as an Inhibitor of Microbial Corrosion of Metal

Guanidinium-containing oligomers, a poorly studied class of organic compounds, have attracted attention due to their bactericidal properties. A guanidinium-containing oligomer based on an aliphatic oligoepoxide is a newly synthesized substance with bactericidal activity, which gives it the prospects for use as a microbial corrosion inhibitor. Aim. The goal of the Читати далі

Mitochondrial dysfunction of the inner membrane of hepatocytes in the development of glutamate-induced steatohepatosis and its correction

Elucidation of the mechanisms of the development of liver steatosis, which are at the heart of the pathogenesis of nonalcoholic fatty liver disease (NAFLD), will allow the introduction of new effective treatment methods into medical practice, as well as the development of new measures for the correction of this disease Читати далі

Comparative toxicological-hygienic assessment, structural-morphological, physicochemical characteristics, and virucidal properties of new nanopowder materials TiO2 and TiO2@Ag

In order to address safety concerns related to the acquisition and utilization of TiO2 and TiO2@Ag nanomaterials, as well as to investigate their disinfectant and biological effects, the structural-morphological, morpho­metry, toxicological, cytotoxic, and virucidal properties of these specified nanomaterials have been studied through experiments conducted on laboratory animals and in Читати далі

Purification and physico-chemical properties of Bacillus atrophaeus protease with elastolytic and fibrinogenolytic activity

Microbial proteases, among which proteases capable of cleaving elastin, fibrin, fibrinogen, and collagen, have been a matter of interest to researchers due to their significant biotechnological potential along with low production cost. We previously showed that Bacillus atrophaeus 08 synthesizes an extracellular protease complex that exhibits high elastolytic, fibrinogenolytic, fibrinolytic Читати далі

Мixed-ligand complexes of germanium – 3d-metal with 1-hydroxyethane-1,1-diphosphonic acid аnd 2,2′-bipyridine as modulators of Bacillus sp. IMV B-7883 elastase and fibrinogenase activity

We have previously shown that Bacillus sp. IMV B-7883 exhibits both elastase and fibrinogenolytic activity. One of the approaches to enhance enzymatic activity is the use of coordination compounds capable to affect enzyme’s activity or synthesis. The purpose of this work was to study the effect of mixed-ligand complexes of Читати далі